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IXIARO
Vaccines
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Drug Name:

IXIARO Rx

Generic Name and Formulations:
Japanese encephalitis virus vaccine; inactivated; aluminum hydroxide adsorbed; susp for IM inj; contains formaldehyde, protamine sulfate; preservative-free.

Company:
Novartis Pharmaceuticals Corp

Therapeutic Use:

Indications for IXIARO:

Japanese encephalitis immunization.

Adult:

≥17yrs: Two doses given 28 days apart. Each dose is 0.5mL IM into deltoid muscle; complete series at least 1 week prior to potential exposure.

Children:

<17yrs: not recommended.

Contraindications:

Severe allergic reaction (eg, anaphylaxis) after a previous dose.

Warnings/Precautions:

Immunodeficiency. Bleeding disorders. Acute febrile illness. Allergy to protamine sulfate. Have epinephrine inj (1:1000) available. Pregnancy (Cat.B). Nursing mothers.

Interactions:

Concomitant vaccines: see literature. Immunosuppressants (eg, radiation, chemotherapy, high-dose steroids): may get suboptimal response.

Pharmacological Class:

Japanese encephalitis vaccine.

Adverse Reactions:

Local reactions (eg, pain, tenderness), headache, myalgia, fatigue, flu-like illness, GI upset, pyrexia.

How Supplied:

Single-dose syringe (0.5mL)—1

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