Acetaminophen in combination with ibuprofen or oxycodone, as well as diclofenac, and flurbiprofen may offer more effective analgesia for acute postoperative dental pain in adults.
The effects of glucosamine supplements in the treatment of patients with painful temporomandibular joint osteoarthritis were not superior to the effects of ibuprofen taken 2 to 3 times per day.
Fifteen percent of adults who took ibuprofen during a 1-week diary study exceeded the maximum recommended daily dose limit.
Nonopioid Analgesic Combination and Opioid Combinations Provide Similar Analgesic Effects for Acute Extremity PainDecember 04, 2017
Nonopioid analgesic combinations may be noninferior to opioid/acetaminophen combinations for reducing acute extremity pain.
Among children who have undergone minor outpatient orthopedic surgery, ibuprofen provides equivalent postoperative pain relief compared with oral morphine.
The repeated dosing of 25 mg low-dose oromucosal ibuprofen provides greater and more rapid pain relief for non-streptococcal sore throat pain than placebo.
Acetaminophen and ibuprofen are frequently under-dosed in children in the emergency department.
Celecoxib is comparable to naproxen and ibuprofen in cardiovascular safety for patients with arthritis at high risk for cardiovascular disease.
Physicians who want to prescribe alternatives for pain management should familiarize themselves with current research.
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