Headache

Intravenous Aminophylline Safe and Effective for Postdural Puncture Headache

Intravenous Aminophylline Safe and Effective for Postdural Puncture Headache

By

Investigators examine the safety and efficacy of intravenous aminophylline for postdural puncture headaches.

Managing Pediatric Migraine: Current Therapies and Future Directions

Managing Pediatric Migraine: Current Therapies and Future Directions

By

Migraine is highly prevalent in children and adolescents, affecting almost 10% of children between 5 and 15 years old and 30% of adolescents between 15 and 19 years old.

NPRS, Neck Disability Index: Reliable Assessment Tools in the Short-Term

NPRS, Neck Disability Index: Reliable Assessment Tools in the Short-Term

By

The Neck Disability Index, and to a lesser extent, the Numeric Pain Rating Scale, may represent reliable measures for patients to self-report cervicogenic headache-associated disability and pain in the short-term.

Migraine Linked With Increased Long-Term Cardiovascular, Cerebrovascular Event Risk

Migraine Linked With Increased Long-Term Cardiovascular, Cerebrovascular Event Risk

By

Migraine headache is associated with a higher risk for major adverse cardiovascular and cerebrovascular events.

Galcanezumab Effective in Phase 3 Episodic Cluster Headache Study

Galcanezumab Effective in Phase 3 Episodic Cluster Headache Study

By

The episodic cluster headache trial included a total of 106 patients with an average of 17.5 cluster headache attacks per week at baseline.

Antidepressant Medications and Headache: Is There a Link?

Antidepressant Medications and Headache: Is There a Link?

By

Compared to placebo, selective serotonin reuptake inhibitors (SSRIs) were associated with a significantly higher risk of headache (risk ratio [RR] 1.06, 95% CI: 1.00 to 1.13; P =.045).

Avoiding Treatment Effect Overestimation in Medication-Overuse Headache

Avoiding Treatment Effect Overestimation in Medication-Overuse Headache

By

A period of observation after an educational session may be important to confirm medication-overuse headache (MOH) diagnoses.

Repeat Masseter NGF Injection May Result in Increased Pain Sensitivity

Repeat Masseter NGF Injection May Result in Increased Pain Sensitivity

By

Repeated injections of nerve growth factor may lead to increased mechanical sensitivity in the masseter — but not in the temporalis muscle — as well as increased entropy.

Eptinezumab for Frequent Episodic Migraine: Results of Phase 3 PROMISE-1 Study

Eptinezumab for Frequent Episodic Migraine: Results of Phase 3 PROMISE-1 Study

By

Eptinezumab, a humanized monoclonal antibody specific to calcitonin gene-related peptide, may be an effective prophylactic for individuals with frequent episodic migraines.

Pain, Psychiatric Comorbidities More Common in Chronic vs Episodic Migraine

Pain, Psychiatric Comorbidities More Common in Chronic vs Episodic Migraine

By

Individuals with chronic vs episodic migraine may be more likely to experience chronic back pain, chronic pain, neck pain, anxiety, and depression.

Erenumab Shown to Reduce Headache Days for Patients with Episodic Migraine

Erenumab Shown to Reduce Headache Days for Patients with Episodic Migraine

By

Researchers assessed the ability of erenumab to decrease the mean number of acute headache days in patients with episodic migraine.

Peripheral Nerve Blocks for Headache Disorders: Expert Roundtable

Peripheral Nerve Blocks for Headache Disorders: Expert Roundtable

By

Although high-quality studies on the use of peripheral nerve blocks for the treatment of headache disorders are scarce, results observed in clinical practice support their use.

OnabotulinumtoxinA May Reduce Headache Days in Chronic Migraine

OnabotulinumtoxinA May Reduce Headache Days in Chronic Migraine

By

Treating chronic migraine with onabotulinumtoxinA may reduce the number of headache days when administered according to the National Institute for Health and Care Excellence guidelines.

Balloon Angioplasty Provides Clinical Relief in Headache-Positive MS

Balloon Angioplasty Provides Clinical Relief in Headache-Positive MS

By

Percutaneous transluminal angioplasty maybe beneficial for reducing headaches in relapsing remitting and secondary progressive multiple sclerosis.

Headache in Older Adults: Unique Causes and Treatments

Headache in Older Adults: Unique Causes and Treatments

By

It is important for clinicians to quickly and accurately determine potential underlying causes and to prescribe treatments that take into account comorbidities and medications that older patients may be taking for them.

C2 Peripheral Nerve Electroacupuncture Effectively Treats Primary Headache

C2 Peripheral Nerve Electroacupuncture Effectively Treats Primary Headache

By

Peripheral nerve field stimulation with electroacupuncture may represent a less invasive mode of treating primary headache.

Medication-Overuse Headache: Risk Factors May Serve as Treatment Progress Indicators

Medication-Overuse Headache: Risk Factors May Serve as Treatment Progress Indicators

By

Factors that were associated with medication overuse headache in this study included high headache-related disability, attempts to escape and avoid stimuli associated with pain, and the use of combination medications.

Patient Develops Thunderclap Headaches After Consuming 'Carolina Reaper'

Patient Develops Thunderclap Headaches After Consuming 'Carolina Reaper'

By

The authors note that this appears to be the first case of RCVS secondary to pepper or cayenne ingestion.

Clinical Vignette: Facial Pain, Headaches, and Neck Pain

Clinical Vignette: Facial Pain, Headaches, and Neck Pain

By

A 39-year-old woman presents with a 2-year history of facial pain, headaches, and neck pain.

Physicians Present Recommendations For and Against Acupuncture for Pain

Physicians Present Recommendations For and Against Acupuncture for Pain

In the approach adopted by NICE, the benefit of acupuncture is compared with sham acupuncture rather than a direct comparison with pharmaceutical treatments.

Undifferentiated Headaches Common in Children, Adolescents

Undifferentiated Headaches Common in Children, Adolescents

By

Researchers introduce and investigate a new category of headache termed undifferentiated headache in a pediatric population.

Evaluating Headache in the Elderly: Primary vs Secondary Causes

Evaluating Headache in the Elderly: Primary vs Secondary Causes

By

Given the unique challenges presented by aging, new cases of headache in older adults should be evaluated carefully for a differential diagnosis of primary headache and to exclude underlying causes of secondary headache.

Factors Associated With Headache Occurrence

Factors Associated With Headache Occurrence

By

Reduced basic psychological need satisfaction, important factors for quality of life perception and encompassing autonomy, competence, and relatedness, was shown to be correlated with headache occurrence.

Bed Rest vs Fluid Supplementation for Postdural Puncture Headache

Bed Rest vs Fluid Supplementation for Postdural Puncture Headache

By

Bed rest is not superior to early mobilization or fluid supplementation for reducing the incidence of postdural puncture headache.

Assessing the Value of Brain MRI in Migraine With Normal Neurologic Exam

Assessing the Value of Brain MRI in Migraine With Normal Neurologic Exam

Routine brain magnetic resonance imaging is not necessary for those with migraine who have normal neurologic function unless there is a clear clinical indication that there are underlying structural abnormalities.

Targeted Group Education for Chronic Headache in Adolescents

Targeted Group Education for Chronic Headache in Adolescents

By

Researchers reviewed survey results to determine whether adolescents with chronic headache might benefit from either a 1-time comprehensive evaluation and management plan or standard care.

Acupuncture, Physiotherapy Combination May Benefit Patients With Tension-Type Headache

Acupuncture, Physiotherapy Combination May Benefit Patients With Tension-Type Headache

By

Patients with tension-type headache experience benefit from acupuncture and stretching, especially in combination with pressure pain threshold physiotherapy hands-on techniques.

Migraine Burden May Be Reduced With Physical Activity

Migraine Burden May Be Reduced With Physical Activity

By

Recent research has found that exercise reduced the burden of migraine and the ability to engage in physical activity by reducing the effect of tension-type headache and neck pain.

Evaluating Day-to-Day Variations in Migraine, Non-Migraine Headaches

Evaluating Day-to-Day Variations in Migraine, Non-Migraine Headaches

By

The frequency, intensity, and daily interference of headaches change over a 6-month period, with day-to-day variation being more volatile in migraine than in non-migraine headaches.

CGRP Antagonist Shows Effectiveness in Acute Migraine

CGRP Antagonist Shows Effectiveness in Acute Migraine

By

Allergan has announced positive Phase 3 trial results for ubrogepant, a novel calcitonin gene-related peptide receptor antagonist for the acute treatment of migraine.

Sign Up for Free e-Newsletters