In the post-hoc analysis, researchers evaluated the time to onset of effect of galcanezumab as well as whether treatment with the study drug was associated with a reduction in migraine headache days.
This randomized, open-label study examined participant reported outcomes, safety, and tolerability of onabotulinumtoxinA and topiramate in adults with chronic migraines.
Polypharmacy in individuals with primary headache may arise out of a prescribing cascade.
A high percentage of cannabis users take the drug to treat headache and probable migraine.
Investigators examine the safety and efficacy of intravenous aminophylline for postdural puncture headaches.
Migraine is highly prevalent in children and adolescents, affecting almost 10% of children between 5 and 15 years old and 30% of adolescents between 15 and 19 years old.
The Neck Disability Index, and to a lesser extent, the Numeric Pain Rating Scale, may represent reliable measures for patients to self-report cervicogenic headache-associated disability and pain in the short-term.
Migraine headache is associated with a higher risk for major adverse cardiovascular and cerebrovascular events.
The episodic cluster headache trial included a total of 106 patients with an average of 17.5 cluster headache attacks per week at baseline.
Compared to placebo, selective serotonin reuptake inhibitors (SSRIs) were associated with a significantly higher risk of headache (risk ratio [RR] 1.06, 95% CI: 1.00 to 1.13; P =.045).
A period of observation after an educational session may be important to confirm medication-overuse headache (MOH) diagnoses.
Repeated injections of nerve growth factor may lead to increased mechanical sensitivity in the masseter — but not in the temporalis muscle — as well as increased entropy.
Eptinezumab, a humanized monoclonal antibody specific to calcitonin gene-related peptide, may be an effective prophylactic for individuals with frequent episodic migraines.
Individuals with chronic vs episodic migraine may be more likely to experience chronic back pain, chronic pain, neck pain, anxiety, and depression.
Researchers assessed the ability of erenumab to decrease the mean number of acute headache days in patients with episodic migraine.
Although high-quality studies on the use of peripheral nerve blocks for the treatment of headache disorders are scarce, results observed in clinical practice support their use.
Treating chronic migraine with onabotulinumtoxinA may reduce the number of headache days when administered according to the National Institute for Health and Care Excellence guidelines.
Percutaneous transluminal angioplasty maybe beneficial for reducing headaches in relapsing remitting and secondary progressive multiple sclerosis.
It is important for clinicians to quickly and accurately determine potential underlying causes and to prescribe treatments that take into account comorbidities and medications that older patients may be taking for them.
Peripheral nerve field stimulation with electroacupuncture may represent a less invasive mode of treating primary headache.
Factors that were associated with medication overuse headache in this study included high headache-related disability, attempts to escape and avoid stimuli associated with pain, and the use of combination medications.
The authors note that this appears to be the first case of RCVS secondary to pepper or cayenne ingestion.
A 39-year-old woman presents with a 2-year history of facial pain, headaches, and neck pain.
In the approach adopted by NICE, the benefit of acupuncture is compared with sham acupuncture rather than a direct comparison with pharmaceutical treatments.
Researchers introduce and investigate a new category of headache termed undifferentiated headache in a pediatric population.
Given the unique challenges presented by aging, new cases of headache in older adults should be evaluated carefully for a differential diagnosis of primary headache and to exclude underlying causes of secondary headache.
Reduced basic psychological need satisfaction, important factors for quality of life perception and encompassing autonomy, competence, and relatedness, was shown to be correlated with headache occurrence.
Bed rest is not superior to early mobilization or fluid supplementation for reducing the incidence of postdural puncture headache.
Routine brain magnetic resonance imaging is not necessary for those with migraine who have normal neurologic function unless there is a clear clinical indication that there are underlying structural abnormalities.
Researchers reviewed survey results to determine whether adolescents with chronic headache might benefit from either a 1-time comprehensive evaluation and management plan or standard care.
Clinical Pain Advisor Articles
- Two Screening Tools May Accurately Predict Transition From Acute to Chronic Low Back Pain
- Tools to Address the Opioid Crisis
- Methamphetamine Use on the Rise in Patients With Opioid Use Disorder
- Patterns of Non-Medical Prescription Opioid Use in Adolescents
- Half of the Responders to Our Poll Agree With the Approval of Dsuvia: We Want to Hear From You
- The Unintended Consequences of the CDC Opioid Guideline According to Pain Management Specialists
- Initial Consultation for Neck Pain May Reduce Opioid Consumption, Healthcare Utilization
- FDA-Approved Test Provides Pharmacogenetic Reports Directly to Consumers
- Set of Interventions May Effectively Reduce Opioid Overprescribing
- Cannabinoid-Associated Analgesia May Be Mediated Through Modulation of Affective Processes
- FDA Panel Votes in Favor of Abuse-Deterrent Oxycodone Reformulation
- FDA Proposes New Restrictions on Sale of Electronic Nicotine Delivery Systems
- Central Sensitization in Greater Trochanteric Pain Syndrome
- Pain Acceptance May Reduce Headache-Related Disability in Migraine
- FDA Issues Safety Alert Regarding Intrathecal Delivery of Pain Meds