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EVISTA
Bone disorders
Breast cancer
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Drug Name:

EVISTA Rx

Generic Name and Formulations:
Raloxifene HCl 60mg; tabs.

Company:
Lilly, Eli and Company

Therapeutic Use:

Indications for EVISTA:

Prevention and treatment of osteoporosis in postmenopausal women.

Adult:

60mg once daily.

Children:

Not recommended.

Contraindications:

Active or history of venous thromboembolic events. Nursing mothers. Pregnancy (Cat.X). Women who may become pregnant.

Warnings/Precautions:

Not for use in premenopausal women. Concomitant systemic estrogen therapy: not recommended. Discontinue 72 hours before, and during prolonged immobilization; resume when fully ambulatory. Coronary heart disease or risk of coronary event (increased risk of death due to stroke). Hepatic dysfunction. Moderate to severe renal impairment.

Interactions:

May antagonize warfarin; monitor. Avoid concomitant cholestyramine, other anion exchange resins. Caution with other highly protein-bound drugs (eg, diazepam, diazoxide, lidocaine).

Pharmacological Class:

Selective estrogen receptor modulator (SERM).

Adverse Reactions:

Hot flashes, leg cramps, peripheral edema, flu syndrome, arthralgia, sweating; rare: venous thromboembolic events.

How Supplied:

Tabs—30, 100, 2000

Indications for EVISTA:

Reduction in risk of invasive breast cancer in postmenopausal women: with osteoporosis and/or at high risk for invasive breast cancer.

Adult:

60mg once daily.

Children:

Not recommended.

Contraindications:

Active or history of venous thromboembolic events. Nursing mothers. Pregnancy (Cat.X). Women who may become pregnant.

Warnings/Precautions:

Not for use in premenopausal women. Concomitant systemic estrogen therapy: not recommended. Discontinue 72 hours before, and during prolonged immobilization; resume when fully ambulatory. Coronary heart disease or risk of coronary event (increased risk of death due to stroke). Hepatic dysfunction. Moderate to severe renal impairment.

Interactions:

May antagonize warfarin; monitor. Avoid concomitant cholestyramine, other anion exchange resins. Caution with other highly protein-bound drugs (eg, diazepam, diazoxide, lidocaine).

Pharmacological Class:

Selective estrogen receptor modulator (SERM).

Adverse Reactions:

Hot flashes, leg cramps, peripheral edema, flu syndrome, arthralgia, sweating; rare: venous thromboembolic events.

How Supplied:

Tabs—30, 100, 2000

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