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ENGERIX-B ADULT
Vaccines
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Drug Name:

ENGERIX-B ADULT Rx

Generic Name and Formulations:
Hepatitis B vaccine (recombinant) 20mcg/mL; aluminum hydroxide adsorbed; IM inj; preservative-free; contains thimerosal (trace).

Company:
GlaxoSmithKline

Therapeutic Use:

Indications for ENGERIX-B ADULT:

Hepatitis B immunization.

Adult:

Give IM in deltoid muscle. 11–19yrs: 10mcg at elected date and repeat 1 and 6 months later, or 20mcg at elected date and repeat 1, 2, and 12 months later, or 20mcg at elected date and repeat 1 and 6 months later. >19yrs: 20mcg at elected date and repeat 1 and 6 months later, or 20mcg at elected date and repeat 1, 2, and 12 months later. Hemodialysis: 40mcg at elected date and repeat 1, 2, and 6 months later. High-risk: consider hepatitis B immune globulin also. Booster dose: when appropriate, may use 20mcg for persons 11yrs of age and older; hemodialysis patients booster dose is 40mcg.

Children:

Give IM in anterolateral thigh or deltoid; see literature. Infants (mothers are HBsAG negative): 10mcg at birth and repeat 1 and 6 months later; infants (mothers are HBsAG positive) and children through age 10yrs: 10mcg at elected date and repeat 1 and 6 months later, or 10mcg at elected date and repeat 1, 2, and 12 months later. High risk: consider hepatitis B immune globulin also. Booster doses: when appropriate, may use 10mcg for children age 10yrs or younger, or 20mcg for ages 11yrs and older.

Contraindications:

Yeast hypersensitivity.

Warnings/Precautions:

May defer in acute febrile illness or active infection. May be given SC only if risk of hemorrhage. Have epinephrine inj available. Multiple sclerosis. Pregnancy (Cat.C). Nursing mothers.

See Also:

ENGERIX-B PEDIATRIC/ADOLESCENT

Pharmacological Class:

HB.

Adverse Reactions:

Local reactions, malaise, nausea, diarrhea, rash. Anaphylaxis.

How Supplied:

Pediatric/Adolescent (single-dose prefilled Tip-Lok syringe)—5 (without needles)
Pediatric/Adolescent (single-dose vials)—1, 10
Adult (single-dose prefilled Tip-Lok syringe)—5 (without needles)
Adult (single-dose vials)—1, 10, 25

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