Diana Ernst

RPh

Most Recent Articles by Diana Ernst

First Generic Versions of Suboxone Get FDA Approval for Opioid Dependence

First Generic Versions of Suboxone Get FDA Approval for Opioid Dependence

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The treatment combines buprenorphine, a partial-opioid agonist, with naloxone, an opioid antagonist.

Olinciguat Granted Orphan Drug Status for Sickle Cell Disease

Olinciguat Granted Orphan Drug Status for Sickle Cell Disease

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Olinciguat is a soluble guanylate cyclase stimulator currently in Phase 2 development.

IV Tramadol Significantly Reduces Post-Op Pain in Phase 3 Study

IV Tramadol Significantly Reduces Post-Op Pain in Phase 3 Study

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In this multicenter, double-blind, placebo-controlled trial, patients (N=409) were randomized 1:1:1 to a postoperative regimen of IV tramadol 50mg, IV tramadol 25mg, or placebo administered over 15 minutes at hours 0, 2, 4, and once every 4 hours thereafter (up to 13 doses).

Lyrica Approved as Adjunctive Tx for Partial Onset Seizures in Children

Lyrica Approved as Adjunctive Tx for Partial Onset Seizures in Children

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The approval was based on a 12-week, double-blind, placebo-controlled study (N=295) in pediatric patients 4-17 years of age.

Patient Develops Thunderclap Headaches After Consuming 'Carolina Reaper'

Patient Develops Thunderclap Headaches After Consuming 'Carolina Reaper'

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The authors note that this appears to be the first case of RCVS secondary to pepper or cayenne ingestion.

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