Neuroinflammation in Neuropathic Pain Indicated by Elevated Levels of Proinflammatory Chemokines in CSFOctober 17, 2017
Patients with neuropathic pain have elevated levels of a set of pro-inflammatory chemokines compared with healthy individuals, suggesting ongoing neuroinflammation.
Patients with myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) were shown to have a differential cytokine signature compared with healthy controls.
Vagus nerve stimulation inhibits cytokine production and reduces inflammation, and may be effective for a subset of RA patients.
Because the increased cytokine levels in the acute phase of herpes zoster are assumed to be a potential mechanism for inducing PHN, the early suppression of these cytokines by LLLT may help prevent the development of PHN.
Caused by dysregulation of inflammatory responses
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