Clinical Research

The Streetlight Effect and Bias in Clinical Research

The Streetlight Effect and Bias in Clinical Research

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Evidence of the streetlight effect can be found across several fields, in which cases investigators draw suspect conclusions from analysis of irrelevant data.

Reducing the <i>P</i>-Value for Statistical Significance to Improve the Quality of Research?

Reducing the P-Value for Statistical Significance to Improve the Quality of Research?

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In a controversial and divisive article, a group of researchers proposes to improve "statistical standards of evidence" by lowering the P value from P <.05 to P <.005 in the fields of biomedical and social sciences.

Reporting Negative Data in Clinical Trial Results

Reporting Negative Data in Clinical Trial Results

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Increasingly, the scientific community is coming to realize the invaluable role that negative outcomes play in the understanding of medicine as a whole.

Informed Consent in Medical Research: A Q&A

Informed Consent in Medical Research: A Q&A

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New methods of obtaining consent are offering options that can bridge the geographic distances between researcher and participant, while making study information more easily accessible.

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