Chronic Pain

Olinciguat Granted Orphan Drug Status for Sickle Cell Disease

Olinciguat Granted Orphan Drug Status for Sickle Cell Disease

By

Olinciguat is a soluble guanylate cyclase stimulator currently in Phase 2 development.

Medical Cannabis Shows Promise in Treating Symptoms of Multiple Sclerosis

Medical Cannabis Shows Promise in Treating Symptoms of Multiple Sclerosis

By

Differing formulations and ratios of the subjects' medical cannabis regimens have been accounted for, though further information about ratios of CBD and TCH are subject to change due to continued ongoing research.

Multiple Sclerosis Pain Common Disruptive Factor in Everyday Activities

Multiple Sclerosis Pain Common Disruptive Factor in Everyday Activities

By

Pain in patients with multiple sclerosis may affect their daily functioning regardless of disease severity.

Development of Chronic Pain Highly Dependent on Pain History

Development of Chronic Pain Highly Dependent on Pain History

By

The development of and recovery from chronic pain was found to be highly dependent on a patient's previous history of pain.

Education Plus Exercise, Single Corticosteroid Injection Effective in Long Term for Gluteal Tendinopathy

Education Plus Exercise, Single Corticosteroid Injection Effective in Long Term for Gluteal Tendinopathy

By

Education combined with exercise as well as a single corticosteroid injection may be more effective than a wait-and-see approach for alleviating gluteal tendinopathy-associated pain.

Opioids in Setting of Hemodialysis Associated With Adverse Events

Opioids in Setting of Hemodialysis Associated With Adverse Events

By

Opioids were found to be associated with adverse events in older Medicare beneficiaries on hemodialysis.

Exposure to Opioids in the ICU May Not Be Associated With Persistent Pain

Exposure to Opioids in the ICU May Not Be Associated With Persistent Pain

By

Persistent pain — which is common in survivors of critical illnesses — may not be associated with opioid exposure during intensive care unit stay.

Catastrophizing and Function in Chronic Spinal Pain

Catastrophizing and Function in Chronic Spinal Pain

By

Pain catastrophizing may be associated with reduced psychological — and to a lesser extent physical —function in patients with neuropathic pain and spinal pain.

Efficacy of Web-Based Pain Empowerment, Self-Management Platform for Chronic Pain

Efficacy of Web-Based Pain Empowerment, Self-Management Platform for Chronic Pain

By

A newly developed Web-based platform designed to empower patients with chronic pain and provide them with self-management tools was found to improve self-efficacy and treatment satisfaction when administered in conjunction with nurse and social worker coaching.

Psychological Interventions May Reduce Pain, Catastrophizing in Elderly

Psychological Interventions May Reduce Pain, Catastrophizing in Elderly

By

Cognitive behavioral therapy-based psychological interventions may provide some benefits in older adults with chronic non-cancer pain.

Marijuana Legalization and Opioid Prescribing Rates

Marijuana Legalization and Opioid Prescribing Rates

By

Implementing medical or adult-use marijuana laws may reduce the rate of opioid prescribing for Medicaid enrollees.

Interbrain Coupling During Handholding Associated With Analgesia, Empathy

Interbrain Coupling During Handholding Associated With Analgesia, Empathy

By

Interbrain coupling of areas implicated in pain processing may be enhanced when romantic partners hold hands while 1 of the 2 is subjected to pain.

The Relationship Between Sleep, Chronic Pain, and Mood Disorders in Children

The Relationship Between Sleep, Chronic Pain, and Mood Disorders in Children

By

The presence of sleep disorders in children with chronic pain may result in greater pain levels and pain interference, a relationship that may in part be mediated by anxiety and depressive symptoms.

Prescription Opioid Tapering in Community Outpatients With Chronic Pain

Prescription Opioid Tapering in Community Outpatients With Chronic Pain

By

Investigators sought to determine whether a patient-centered prescription opioid tapering program would be effective for reducing opioid doses in patients taking long-term prescription opioids.

Predicting Suicidal Ideation in Veterans With Chronic Pain

Predicting Suicidal Ideation in Veterans With Chronic Pain

By

A number of factors including chronic pain co-occurring with posttraumatic stress disorder and pain interference may predict suicidal ideation and violent impulses in US veterans with chronic pain.

Elder Abuse Not Associated With Risk for Chronic Pain

Elder Abuse Not Associated With Risk for Chronic Pain

Researchers assessed the cross-sectional and longitudinal relationships between elder abuse and neglect and chronic pain.

Assessing Outcomes of Acceptance and Commitment Therapy for Chronic Pain

Assessing Outcomes of Acceptance and Commitment Therapy for Chronic Pain

By

Neuropsychological performance may not be associated with the improvements in pain interference observed after an 8-week Acceptance and Commitment Therapy program in veterans with chronic pain.

Tackling the Chronic Pain and Opioid Use Disorder Crises Through Public-Private Partnerships

Tackling the Chronic Pain and Opioid Use Disorder Crises Through Public-Private Partnerships

By

Partnerships between public and private entities could expedite the development of nonaddictive pain therapies and other strategies to address the dual crises of chronic pain and opioid use disorder.

Helping to End Addiction Long-Term Initiative by NIH Launched to Address Opioid Epidemic

Helping to End Addiction Long-Term Initiative by NIH Launched to Address Opioid Epidemic

By

National Institutes of Health Director, Francis Collins, MD, PhD, announced on April 4, 2018 the launch of the Helping to End Addiction Long-Term Initiative.

Pernix Announces Availability of Zohydro ER 20 mg Dosage Strength

Pernix Announces Availability of Zohydro ER 20 mg Dosage Strength

By

Zohydro ER is also available in 10mg, 15mg, 30mg, 40mg, and 50mg dosage strengths.

Positive Affect, Resilience, and Pain in MS With Chronic Pain

Positive Affect, Resilience, and Pain in MS With Chronic Pain

By

Resilience may mediate the relationships between positive affect and pain interference and depression in patients with multiple sclerosis.

Chronic Pain in Adolescents and Alexithymia

Chronic Pain in Adolescents and Alexithymia

By

Adolescent patients with chronic pain may be more likely to suffer from alexithymia.

CBT vs Pain Education for Chronic Pain in Low-Income Clinics

CBT vs Pain Education for Chronic Pain in Low-Income Clinics

By

Group cognitive behavioral therapy and pain education may be more effective than usual care for improving pain and physical function in patients presenting with chronic pain at low-income clinics.

Safety, Efficacy of Lidocaine Infusion for Prolonged Neuropathic Pain

Safety, Efficacy of Lidocaine Infusion for Prolonged Neuropathic Pain

By

Investigators sought to determine whether repeated intravenous low-dose lidocaine could provide prolonged pain relief in patients with refractory neuropathic pain.

Literacy-Adapted Group CBT for Chronic Pain

Literacy-Adapted Group CBT for Chronic Pain

For patients with chronic pain, literacy-adapted group cognitive behavioral therapy and group pain education improve pain and physical function compared with usual care.

Naldemedine Safe, Effective for Opioid-Induced Constipation

Naldemedine Safe, Effective for Opioid-Induced Constipation

By

Naldemedine was found to be safe and effective for increasing bowel movement frequency and improving quality of life in patients with chronic non-cancer pain and opioid-induced constipation.

Limited Evidence Supporting Effectiveness of Cranial Electrical Stimulation for Chronic Pain

Limited Evidence Supporting Effectiveness of Cranial Electrical Stimulation for Chronic Pain

Researchers reviewed evidence relating to the benefits and harms of cranial electrical stimulation for adults with chronic painful conditions, depression, anxiety, and insomnia.

Reviewing the Effectiveness of Lidocaine for the Management of Chronic Pain

Reviewing the Effectiveness of Lidocaine for the Management of Chronic Pain

By

Systemic lidocaine administered via IV or patch has consistently shown effectiveness for the treatment and prevention of chronic pain.

Burden Associated With Pharmacotherapy Switching in Trigeminal Neuralgia

Burden Associated With Pharmacotherapy Switching in Trigeminal Neuralgia

By

An examination of treatment patterns among patients with trigeminal neuralgia suggests that this orofacial disorder appears to be significantly burdensome.

Web-Based CBT Adjunct May Address Aberrant Drug-Related Behaviors in Chronic Pain

Web-Based CBT Adjunct May Address Aberrant Drug-Related Behaviors in Chronic Pain

By

A web-based cognitive behavior therapy program may be associated with greater reductions in aberrant drug-related behavior, pain interference, and pain catastrophizing in patients with chronic pain treated with opioids who undergo treatment as usual compared with patients who undergo treatment as usual only.

Sign Up for Free e-Newsletters