Chronic Pain

Persistent Pain Linked With Greater Memory Decline & Dementia Probability

Persistent Pain Linked With Greater Memory Decline & Dementia Probability

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Older adults with persistent pain showed more rapid memory decline and greater dementia probability compared with adults without persistent pain.

First-in-Class Chronic Pain Drug Candidate Fast Tracked

First-in-Class Chronic Pain Drug Candidate Fast Tracked

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Tanezumab is a NGF inhibitor and is a first-in-class agent to receive Fast Track approval.

Long-Term Opioids Associated With Worse Functional Status, Adverse Events in Polyneuropathy

Long-Term Opioids Associated With Worse Functional Status, Adverse Events in Polyneuropathy

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Polyneuropathy may increase the likelihood of patients receiving long-term opioid therapy.

Online Cognitive Behavioral Pain Management Course May Benefit Fibromyalgia

Online Cognitive Behavioral Pain Management Course May Benefit Fibromyalgia

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This is especially important given that patients with fibromyalgia have difficulty attending treatment sessions in person.

Strategies to Prevent the Transition From Postoperative Acute Pain to Chronic Pain

Strategies to Prevent the Transition From Postoperative Acute Pain to Chronic Pain

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A number of shortcomings are associated with systematic reviews and meta-analyses of postoperative care.

Abuse-Deterrent Extended-Release Morphine Sulfate Launched for Chronic Pain

Abuse-Deterrent Extended-Release Morphine Sulfate Launched for Chronic Pain

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Egalet announced the launch of Arymo ER extended-release tablets for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment.

Opioids for Chronic Pain: New VA/DoD Clinical Guideline

Opioids for Chronic Pain: New VA/DoD Clinical Guideline

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A new clinical practice guideline regarding the use of opioids for chronic pain has been released by the VA and DoD.

Opioid Prescribing: Interventions to Improve Guideline Adherence

Opioid Prescribing: Interventions to Improve Guideline Adherence

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A training program on opioid prescribing for general practice registrars was developed to improve adherence to guidelines on opioid prescribing for chronic noncancer pain.

Measuring Clinically Meaningful Outcomes in Chronic Pain Clinical Trials

Measuring Clinically Meaningful Outcomes in Chronic Pain Clinical Trials

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Standardized and clinically meaningful outcome measures in clinical trials in chronic pain may enhance efforts to develop effective treatments for chronic pain patients.

Biopsychosocial Treatment for Functional Pain Syndromes

Biopsychosocial Treatment for Functional Pain Syndromes

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An individual's pain experience depends on a complex interaction between various biological, environmental, psychological, and societal factors.

The Empower Veterans Program

The Empower Veterans Program

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The Empower Veterans Program was created by the Atlanta Veterans Administration Medical Center to improve quality of life through active self-care in veterans with chronic pain.

Pain Center Crisis: How the Healthcare Community Coped

Pain Center Crisis: How the Healthcare Community Coped

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Dr Stacey sought to highlight how the healthcare community reacted to and coped in the aftermath of the closing of the Seattle Pain Center, by coming together as a team and mobilizing state resources.

Narcotic Analgesic Formulations

Comparative chart of narcotic analgesics including formulations, strengths, and dosing intervals.

A Link Between Altered Reward Processing and Later Pain Complaints?

A Link Between Altered Reward Processing and Later Pain Complaints?

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Reward feedback responses in the brain may be predictive of chronic pain complaints later on.

Discontinuing Opioids in Patients With, Without Substance Use Disorders

Discontinuing Opioids in Patients With, Without Substance Use Disorders

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Most patients (85%) who discontinued long-term opioid use did so because of a clinician's, rather than a patient decision.

Viewing Photographs Reduces Pain Ratings in Patients With Chronic Pain

Viewing Photographs Reduces Pain Ratings in Patients With Chronic Pain

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Viewing photographs can decrease pain intensity in patients with chronic pain.

Resources for Managing Patients With Chronic Pain

Resources for Managing Patients With Chronic Pain

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Clinical Pain Advisor interviewed Penney Cowan, founder and chief executive officer of the ACPA to learn more about the importance of the ACPA's resource for HCPs.

Effects of Pain Interference in Children With Chronic Pain

Effects of Pain Interference in Children With Chronic Pain

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Pain interference was found to mediate the relationship between pain and depression in children with chronic pain.

Customized CBT for HCV Patients Reduces Pain and Substance Use

Customized CBT for HCV Patients Reduces Pain and Substance Use

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A targeted form of CBT is effective in treating chronic pain and substance use disorder in veterans with hepatitis C virus infection.

Abuse-Deterrant Opioids

Compare the abuse deterrent mechanism, special risk groups, contraindications, and warnings/precautions for FDA approved opioids.

Opioids vs NSAIDs Following Motor Vehicle Collision

Opioids vs NSAIDs Following Motor Vehicle Collision

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Opioids prescribed for pain following a motor vehicle collision do not reduce the likelihood of developing persistent pain.

Rapidly Increasing Opioid Dose Raises Risk for New-Onset Depression

Rapidly Increasing Opioid Dose Raises Risk for New-Onset Depression

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Rapid increases in prescription opioid dose may lead to higher rates of new-onset depression.

Diagnostic Criteria for Chronic Sickle Cell Disease-Related Pain

Diagnostic Criteria for Chronic Sickle Cell Disease-Related Pain

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A new evidence-based classification system for chronic sickle cell disease pain was recently published.

Spinal Cord Stimulation to Reduce Opioid Use in Chronic Pain

Spinal Cord Stimulation to Reduce Opioid Use in Chronic Pain

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Spinal cord stimulation was found to help decrease or stabilize opioid use in patients with chronic pain.

Three Upcoming Pain Drugs

Three Upcoming Pain Drugs

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Pharmaceutical companies are working to develop non-opioid drugs for chronic and postoperative pain.

Impact of Patient Perception of Provider Concern on Chronic Pain

Impact of Patient Perception of Provider Concern on Chronic Pain

For patients with chronic pain receiving opioids, provider satisfaction is not associated with functional outcomes.

Assessment of Single-Entity Hydrocodone's Otological Safety

Assessment of Single-Entity Hydrocodone's Otological Safety

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Many analgesics and analgesic combinations for chronic pain have shown temporary and permanent otological effects, including hearing loss.

Intrathecal Therapy for Pain: Updated Guidelines

Intrathecal Therapy for Pain: Updated Guidelines

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The Polyanalgesic Consensus Conference updated guidelines regarding the treatment of pain via intrathecal therapy.

Can Yoga Improve Back-Related Function in Chronic Low Back Pain?

Can Yoga Improve Back-Related Function in Chronic Low Back Pain?

Yoga only led to moderate improvements compared with exercise or no exercise interventions in patients with low back pain.

Pain in Veterans is More Prevalent and Severe Than in Non-Veterans

Pain in Veterans is More Prevalent and Severe Than in Non-Veterans

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It may be that some veterans would benefit from a revised pain management plan with an emphasis on patient-centered care.

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