Chronic Low Back Pain

Extended-Release Oxycodone Efficacious for Chronic Low Back Pain

Extended-Release Oxycodone Efficacious for Chronic Low Back Pain

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Abuse-deterrent extended-release oxycodone (Xtampza® ER; Collegium Pharmaceutical) provided adequate pain relief for patients with chronic low back pain who were previously receiving immediate-release oxycodone.

Physiotherapy and Stabilization Effective in Chronic Low Back Pain

Physiotherapy and Stabilization Effective in Chronic Low Back Pain

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Physiotherapy combined with routine or stabilization exercises is effective for reducing pain and improving muscle dimensions in patients with nonspecific chronic low back pain.

Gabapentinoids: Evaluating the Benefits for Chronic Low Back Pain

Gabapentinoids: Evaluating the Benefits for Chronic Low Back Pain

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Gabapentinoid use presents significant risk for adverse events and provides few benefits for patients with chronic low back pain.

Chronic Low Back Pain: Predicting Treatment Outcomes

Chronic Low Back Pain: Predicting Treatment Outcomes

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Early pain response to duloxetine predicts better outcomes in patients with chronic low back pain.

Radiofrequency Denervation Ineffective for Chronic Low Back Pain

Radiofrequency Denervation Ineffective for Chronic Low Back Pain

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Radiofrequency denervation may be ineffective in alleviating chronic low back pain.

Radiofrequency Denervation for Facet Joint Arthropathy-Related Low Back Pain

Radiofrequency Denervation for Facet Joint Arthropathy-Related Low Back Pain

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Radiofrequency denervation improved chronic low back pain arising from the facet joints.

Disc Replacement Surgery for Low Back Pain Improves Long-Term Outcomes

Disc Replacement Surgery for Low Back Pain Improves Long-Term Outcomes

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Long-term, clinically important improvement in chronic low back pain can be achieved with lumbar total disc replacement and multidisciplinary rehabilitation in patients whose low back pain does not respond to conservative therapy.

First-in-Class Chronic Pain Drug Candidate Fast Tracked

First-in-Class Chronic Pain Drug Candidate Fast Tracked

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Tanezumab is a NGF inhibitor and is a first-in-class agent to receive Fast Track approval.

Intradiscal Steroid Injection Provides Short-Term Relief From Low Back Pain

Intradiscal Steroid Injection Provides Short-Term Relief From Low Back Pain

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A single glucocorticoid intradiscal injection provided relief from low back pain at 1, but not 12 months in patients with active discopathy.

First-in-Class Opioid Analgesic Results for Chronic Back Pain

First-in-Class Opioid Analgesic Results for Chronic Back Pain

Nektar Therapeutics announced positive results from the SUMMIT-07 Phase 3 study of NKTR-181 for the treatment of moderate-to-severe chronic pain.

Managing Spinal Pain With NSAIDs?

Managing Spinal Pain With NSAIDs?

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Meta-analysis indicates short-term NSAID use is generally safe and can relieve pain, but lacks clinically important benefits.

Alleviating Chronic Back Pain With Basivertebral Nerve Ablation

Alleviating Chronic Back Pain With Basivertebral Nerve Ablation

For patients with chronic lumbar back pain, ablation of the basivertebral nerve improves self-reported outcome.

Efficacy of Lumbopelvic Stabilization Training for Low Back Pain

Efficacy of Lumbopelvic Stabilization Training for Low Back Pain

Lumbopelvic stabilization training provides therapeutic effects on chronic nonspecific low back pain conditions.

Could Open-Label Placebo Have an Analgesic Effect?

Could Open-Label Placebo Have an Analgesic Effect?

"Our study shows that clinically significant placebo effects can be produced even when patients are told that they are being given placebos."

FDA Approves Nerve Ablation Device for Low Back Pain

FDA Approves Nerve Ablation Device for Low Back Pain

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Though these initial findings seem promising, the utility of the device may be limited to a small number of patients, according to Steven P. Cohen, MD.

Are Muscle Relaxants Effective for Treating Low Back Pain?

Are Muscle Relaxants Effective for Treating Low Back Pain?

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Meta-analysis shows muscle relaxants are effective in reducing acute but not chronic low back pain.

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