Central Sensitization

Allodynia and Pericranial Tenderness Highly Prevalent in Pediatric Patients With Migraine

Allodynia and Pericranial Tenderness Highly Prevalent in Pediatric Patients With Migraine

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Symptoms associated with central sensitization are common in children and adolescents with migraine.

Greater Trauma Associated With Amplification of Pain, Spinal Nociception

Greater Trauma Associated With Amplification of Pain, Spinal Nociception

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Trauma exposure plays a significant role in both pain response and development of chronic pain.

Chronic Tension-Type Headaches: Pain Extent Associated With Emotional, Physical Burden

Chronic Tension-Type Headaches: Pain Extent Associated With Emotional, Physical Burden

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Greater pain extent of chronic tension-type headaches correlates with older age and with greater emotional and physical burdens in patients.

Secondary Hyperalgesia Mediated by Nociceptive and Other Sensory Pathways

Secondary Hyperalgesia Mediated by Nociceptive and Other Sensory Pathways

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The effects of central sensitization extend beyond nociceptive pathways to other sensory modalities.

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