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CARDURA
Benign prostatic hyperplasia/urinary retention
Hypertension
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Drug Name:

CARDURA Rx

Generic Name and Formulations:
Doxazosin (as mesylate) 1mg, 2mg, 4mg, 8mg; scored tabs.

Company:
Pfizer Inc.

Therapeutic Use:

Indications for CARDURA:

BPH.

Adult:

Initially 1mg once daily; may double dose every 1–2 weeks; max 8mg/day.

Children:

Not applicable.

Warnings/Precautions:

Severe hepatic impairment: not recommended. Monitor blood pressure and for orthostatic hypotension initially and if dose increased. Syncope. Cataract surgery (intraoperative floppy iris syndrome possible). Exclude prostate cancer.

Pharmacological Class:

Alpha-1 blocker.

Adverse Reactions:

Dizziness, fatigue, hypotension, edema, dyspnea; rare: priapism.

How Supplied:

Tabs—100

Indications for CARDURA:

Hypertension.

Adult:

Initially 1 mg once daily. Titrate gradually (based on standing BP at 2–6 hours and 24 hours post-dose) at 2-week intervals if needed; max 16 mg/day.

Children:

Not established.

Warnings/Precautions:

Severe hepatic impairment: not recommended. Monitor for orthostatic hypotension initially and if dose increased. Cataract surgery (intraoperative floppy iris syndrome possible). Pregnancy (Cat.C). Nursing mothers.

Interactions:

Caution when adding other antihypertensives.

Pharmacological Class:

Alpha-1 blocker.

Adverse Reactions:

Syncope (esp. 1st dose and with increased doses), dizziness, somnolence, fatigue/malaise, edema, rhinitis, abnormal vision, tinnitus, epistaxis, orthostatic hypotension, sexual dysfunction, polyuria, urinary incontinence, ataxia, leukopenia, neutropenia, arrhythmia; rare: priapism.

How Supplied:

Tabs—100

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