There is currently little conclusive evidence to suggest a benefit of cannabis use for the management of neuropathic pain.
Medical marijuana laws may be connected to increased rates of illicit cannabis use and cannabis use disorder, leading some users to experience negative consequences, such as motor vehicle accidents.
Interventions targeted at improving medication adherence might mitigate the adverse effects of cannabis use on psychosis outcomes.
Selective cannabinoids may provide limited relief from chronic neuropathic pain and improvements in quality of life and sleep.
Medical marijuana, as a botanical and a scheduled drug does not fit the FDA paradigm for drug approval, a major impediment to its use in research.
Cannabis use disorder is also rising faster in states with legalization laws
A study indicates a likely causal relationship between cannabis use and increased risk for schizophrenia.
In a study of outpatients with depression, researchers found that marijuana use was common and associated with poor recovery.
Most patients (85%) who discontinued long-term opioid use did so because of a clinician's, rather than a patient decision.
In January 2017, the National Academies of Sciences, Engineering, and Medicine released a report titled "The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendation for Research."
Recent studies show that THC consumption affects the dopamine system.
"The utility of the crystal structure may provide inspiration for drug design toward refining efficacy and avoiding adverse events."
These data implicate the cannabinoid system in decision-making regarding the allocation of cognitive effort
Researchers find male users report greater benefits compared to women
New guideline addresses cancer-related chronic pain
Advising patients on strains, explaining limitations
Vaporized cannabis had a significant analgesic response over placebo.
Pot-related poison control calls and hospital discharges spike with wider availability.
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