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Cabergoline
Pituitary disorders
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Drug Name:

Cabergoline Rx

Generic Name and Formulations:
Cabergoline 0.5mg; scored tabs.

Company:
Various generic manufacturers

Therapeutic Use:

Indications for Cabergoline:

Hyperprolactinemic disorders, either idiopathic or due to pituitary tumors.

Adult:

Initially 0.25mg twice weekly. Dose may be increased at 4-week intervals by 0.25mg twice weekly. Max: 1mg twice weekly.

Children:

Not recommended.

Contraindications:

Uncontrolled hypertension. Sensitivity to ergot alkaloids.

Warnings/Precautions:

Not for pregnancy-induced hypertension or postpartum lactation inhibition or suppression. Respiratory or cardiac disease due to fibrosis. Hepatic dysfunction. Pregnancy (Cat.B). Nursing mothers: not recommended.

Interactions:

Concurrent dopamine D2 antagonists (eg, phenothiazines, butyrophenones, thioxanthines, metoclopramide): not recommended. Hypotension may be potentiated by antihypertensives.

Pharmacological Class:

Dopamine agonist.

Adverse Reactions:

GI upset, dizziness, fatigue, postural hypotension, nervousness, breast pain, dysmenorrhea, vision abnormalities; rare: fibrosis, valvulopathy.

Note:

Formerly known under the brand name Dostinex.

How Supplied:

Contact supplier.

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