Ampicillin sodium Injection Rx
Generic Name and Formulations:
Ampicillin sodium 125mg, 250mg, 500mg, 1g, 2g, 10g; per vial; pwd for IV or IM inj after reconstitution and dilution.
Various generic manufacturers
Indications for Ampicillin sodium Injection:
Adults and Children:
Give IV inj slowly over at least 10–15 minutes; rapid IV administration may result in convulsive seizures. Respiratory tract and soft tissue infections: <40kg: 25–50mg/kg per day in equally divided doses every 6–8 hours. ≥40kg: 250–500mg every 6 hours. GI or GU tract infections (including N. gonorrhoeae in women): <40kg: 50mg/kg per day in equally divided doses every 6–8 hours. ≥40kg: 500mg every 6 hours. Urethritis in males due to N. gonorrhoeae: two doses of 500mg each at interval of 8–12 hours. Meningitis: Initiate with IV drip, then continue IM. 150–200mg/kg per day in equally divided doses every 3–4 hours. Septicimia: Initiate IV for at least 3 days, then continue IM every 3–4 hours. 150–200mg/kg per day; treat for at least 10 days if caused by Group A β-hemolytic streptococci.
Cephalosporin, imipenem, other allergy or mononucleosis: not recommended. Monitor blood, renal, and liver function in long-term use. Pregnancy (Cat.B). Nursing mothers.
May cause false (+) glucose test with Clinitest, Benedict's or Fehling's soln. Potentiated by probenecid. May increase risk of rash with allopurinol.
Anaphylaxis, urticaria, GI upset, blood dyscrasias.
Formerly known under the brand names Principen, Totacillin, Pfizerpen-A, Penbritin, Omnipen, Amcill (caps, susp); Polycillin-N, Totacillin-N, Penbritin-S, Omnipen-N (inj).
Clinical Pain Advisor Articles
- Brain Plasticity in Patients With Complex Regional Pain Syndrome
- Chronic Pain Associated With Traumatic Brain Injury: Causes and Management
- Perturbation-Based Rehabilitation Effective for Chronic Low Back Pain
- Migraine Frequency Correlated With Depression and Anxiety
- IBS-Associated Chronic Pain: Formulation of Core Diagnostic Criteria
- Cannabis Use Associated With Aberrant Drug Behaviors
- Walgreens to Carry Naloxone in All Pharmacies to Combat Drug Abuse
- Independent Pharmacies Expanding Services Available to Patients
- Ketamine Exhibits Effective Pain Relief for Refractory Headaches
- Pain In Elite Athletes: IOC Recommendations on Contributing Factors and Treatment Approach
- Naproxen Plus Muscle Relaxants vs Naproxen Monotherapy for Low Back Pain
- Pain Processing: Examining the Role of Oxytocin
- Short- vs Long-Acting Opioids for Osteoarthritis Pain
- Extended-Release Naltrexone Injections Reduce Opioid Dependence
- Depressive Symptoms in Medical Interns Increased With Work-Family Conflicts